The Air 2S is fully supported and hundreds of flights per day are done without issue.
Make sure you most recent flight logs are synced with Maps Made Easy so we can actually see what is going on but my guess would be it is related to touching the control sticks which will end the programmed flight. There is a message that is shown that tells you this will happen and another message is shown to tell you after it happened. Other than that, we would need the log files in Maps Made Easy to see what is really going on.